Latest in Cardiology from ACC.org

• Does Number of CVD Risk Factors Influence Plaque Vulnerability in ACS?
  The number of cardiovascular risk factors was strongly associated with greater plaque vulnerability, especially for culprit lesions, in patients with acute coronary syndromes (ACS), according to new research published in JACC.
• Better Cardiac Outcomes With Missense LMNA Variants Than Truncating Variants
  Truncating LMNA variants are associated with worse arrhythmic outcomes regardless of variant location, whereas missense variants affecting the tail domain and located in exons 7-12 have better arrhythmic and heart failure (HF) outcomes...
• SURMOUNT-5: Greater Loss of Weight, Waist Circumference With Tirzepatide Than Semaglutide
  Tirzepatide leads to significantly greater loss of weight and weight circumference compared with semaglutide among adults with obesity but without diabetes, according to new results from the SURMOUNT-5 phase 3b trial, published in The New England Journal of Medicine.
• Higher Survival Benefit After 2018 U.S. Heart Transplantation Allocation Policy Change
  The 2018 U.S. heart allocation policy change has resulted in an increased survival benefit of heart transplantation due to improved stratification and prioritization of transplant candidates, according to a study published July 7 in JACC: Heart Failure.
• Deep Learning in Automating Cardiac Imaging: Challenges and Mitigation Strategies
  When applying imaging analysis based on deep learning (DL) models, training data and generalization were found to challenge the performance of DL algorithms for automated cardiac measurements, while evaluation metrics were found to challenge the ability to detect underperforming algorithms...