Latest in Cardiology from ACC.org

• FXN Gene Therapy Shows Promise in Treating Patients With FA Cardiomyopathy
  In patients with Friedreich ataxia (FA) cardiomyopathy, intravenous administration of AAVrh.10hFXN, an rh.10 serotype cardiotropic adenoassociated virus vector expressing the normal human FXN coding sequence, was well tolerated and showed promise as a potential treatment...
• Resistance Training Associated With Lower Risk of T2D in US Adults
  Consistent resistance training (RT) may be an important component of type 2 diabetes (T2D) prevention recommendations, especially when combined with adequate aerobic activity and limited sedentary behavior, according to a prospective cohort study published June 22 in JAMA.
• Eagle’s Eye View: Can Resistance Training Lower CV Risk?
  In this week’s View, Dr. Eagle reviews 21-year follow-up data from the Diabetes Prevention Program (DPP), showing that lifestyle intervention—but not metformin—reduces multimorbidity risk in prediabetes.
• Single vs. Double TSP in AFib Ablation Yields Comparable Outcomes | NCDR Study
  Among patients undergoing atrial fibrillation (AFib) ablation, single and double transeptal puncture (TSP) exhibited similar procedural safety and likelihood of discharge in sinus rhythm, according to a recent study published in the Journal of Interventional Cardiac Electrophysiology.
• Genotype Independently Predicts HF Outcomes in Patients With HCM
  In patients with hypertrophic cardiomyopathy (HCM), genotype, peak VO2, log NT-proBNP and LVEF independently predict heart failure (HF) outcomes, and combining these measures identified patients at higher risk of HF-related death or transplant, according to a recent study published in JACC: Heart Failure.