Latest in Cardiology from ACC.org

• Print Publication of ZENITH and SOUL Trials Spark Continued Dialogue
  The print publication of the ZENITH and SOUL trials – originally presented and published online during ACC.25 in Chicago – provides an additional platform for editorial commentary on their broader implication.
• ACC Submits Comments on FY 2026 IPPS Proposed Rule
  The ACC submitted written comments on June 4 to the Centers for Medicare and Medicaid Services (CMS) on the fiscal year (FY) 2026 Inpatient Prospective Payment System (IPPS) proposed rule.
• CV and Bleeding Effects Comparable For Aspirin vs. Clopidogrel in Patients With ACS Within 1 Year Post PCI
  Compared with clopidogrel monotherapy, cardiovascular and bleeding outcomes were similar with aspirin monotherapy beyond one month and up to one year after PCI in patients with acute coronary syndromes (ACS), whether or not they were at high bleeding risk (HBR) or had a STEMI or NSTE-ACS...
• Single-Dose Zilebesiran Injection Plus Antihypertensive Drug Reduces SBP
  A subcutaneous injection of the novel drug zilebesiran, when added to a standard antihypertensive agent, significantly reduces both 24-hour mean ambulatory and office systolic blood pressure (SBP) compared with placebo at three months in patients with uncontrolled hypertension...
• Studies Offer New Insight Into LBBAP Mechanisms
  Two studies recently published in JACC: Clinical Electrophysiology draw a sharp focus on modalities of left bundle branch area pacing (LBBAP), including left bundle branch pacing (LBBP) and left ventricular septal pacing (LVSP), as well as expand the current understanding of underlying physiological mechanisms.