Latest in Cardiology from ACC.org

• EWAS Identifies Associations Between DNA Methylation, Atherosclerosis
  An epigenome-wide association study (EWAS) identified a large number of associations between DNA methylation and carotid, coronary and peripheral atherosclerosis, with >90% of sites traceable to the epigenetic signatures of cardiovascular risk factors, predominantly smoking, according to research published June 3 in JACC.
• ACC Urges Changes as Ambulatory Specialty Model Approaches 2027 Launch
  With the mandatory Ambulatory Specialty Model (ASM) for Heart Failure (HF) slated to begin Jan. 1, 2027, the ACC is prioritizing member awareness and education, while pressing the Centers for Medicare and Medicaid Services (CMS) to address key issues with the model's design and requirements.
• Incorrect Specialty Classifications Identified in ASM Participant List
  An ACC analysis of the preliminary participant list for the Ambulatory Specialty Model (ASM) for Heart Failure found that up to 20% of selected cardiologists may be incorrectly classified under the specialty cardiovascular disease/cardiology.
• AI-Enabled Clinician: Navigating Large Language Models in Cardiology
  In this episode, Chief Innovation Officer Dr. Ami Bhatt and Dr. Ankeet Bhatt explore the impact of large language models (LLM) on cardiovascular care today.
• New Research Shows Benefits of Evolocumab, Laroprovstat
  Three new studies published in Circulation highlight advances in lipid-lowering therapy, with early-stage data supporting a first-in-class oral PCSK9 inhibitor and two separate analyses showing that evolocumab reduces major cardiovascular events across a range of high-risk patients, including those with elevated Lp(a) and those with prior PCI but no history of MI.